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COVID-19 Frontline TeleECHO Series: A New Light in the Darkness: Therapies Recently Granted Emergency Use Authorizations for Patients with COVID-19

When:
February 1, 2021 @ 12:00 pm – 1:00 pm
2021-02-01T12:00:00-05:00
2021-02-01T13:00:00-05:00

COVID-19 Frontline TeleECHO Series: A New Light in the Darkness: Therapies Recently Granted Emergency Use Authorizations for Patients with COVID-19

Monday, February 1, 2021

12:00 PM – 1:00 PM ET

Faculty:

Shyam Kottilil, MD, PhD

Professor of Medicine
Chief, Division of Infectious Diseases
Institute of Human Virology
University of Maryland
Baltimore, MD

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Updates in the Treatment and Prevention of COVID-19​

Molnupiravir, an Oral Antiviral, Reduced the Risk of Hospitalization or Death in Patients with Mild-to-Moderate COVID-19

Molnupiravir, an investigational oral antiviral medicine, significantly reduced the risk of hospitalization or death by 50% in an interim analysis of the phase 3 MOVe-OUT trial. The planned analysis evaluated data from 775 at-risk, non-hospitalized adult patients with mild-to-moderate COVID-19. All patients enrolled had at least one risk factor associated with poor COVID-19 outcomes and were randomized within 5 days of symptom onset. At day 29, 7.3% of patients who received molnupiravir were either hospitalized or died, compared with 14.1% of placebo-treated patients (P= .0012). No deaths were reported in patients receiving molnupiravir, compared with 8 deaths in patients who received placebo. The incidence of any adverse event was comparable in the molnupiravir and placebo groups (35% and 40%, respectively). Discontinuation due to adverse events was lower with molnupiravir (1.3%) versus placebo (3.4%).

Reference:

https://www.contagionlive.com/view/molnupiravir-could-become-first-authorized-covid-19-pill